Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons.
Insulin/insulin-like growth factor (IGF) signaling constitutes an evolutionarily conserved pathway that controls growth, energy homeostasis, and longevity. In Drosophila melanogaster, key components of this pathway are the insulin-like peptides (Dilps). The major source of Dilps is a cluster of larg...
Main Authors: | Clements, J, Hens, K, Francis, C, Schellens, A, Callaerts, P |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Mutational analysis of the eyeless gene and phenotypic rescue reveal that an intact Eyeless protein is necessary for normal eye and brain development in Drosophila.
by: Clements, J, et al.
Published: (2009) -
Pax6 and eye development in Arthropoda.
by: Callaerts, P, et al.
Published: (2006) -
Glial and Neuronal Neuroglian, Semaphorin-1a and Plexin A Regulate Morphological and Functional Differentiation of Drosophila Insulin-Producing Cells
by: Jason Clements, et al.
Published: (2021-07-01) -
Genome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells.
by: Mattias Winant, et al.
Published: (2022-09-01) -
Co-orthology of Pax4 and Pax6 to the fly eyeless gene: molecular phylogenetic, comparative genomic, and embryological analyses.
by: Manousaki, T, et al.
Published: (2011)