Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.

Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.

OBJECTIVE: To assess the genetic association of pain in patients with knee osteoarthritis (OA) and those with multiple regional pain with the R1150W variant in the α-subunit of the voltage-gated sodium channel Na(V)1.7. METHODS: Knee OA patients from 2 UK cohorts (1,411 from the Genetics of Osteoart...

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Autori principali:	Valdes, A, Arden, N, Vaughn, F, Doherty, SA, Leaverton, P, Zhang, W, Muir, K, Rampersaud, E, Dennison, E, Edwards, M, Jameson, K, Javaid, M, Spector, T, Cooper, C, Maciewicz, R, Doherty, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2011

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