Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele.

Impaired regulation of neuronal nitric oxide synthase and heart rate during exercise in mice lacking one nNOS allele.

We tested the hypothesis that a single allele deletion of neuronal nitric oxide synthase (nNOS) would impair the neural control of heart rate following physical training, and that this phenotype could be restored following targeted gene transfer of nNOS. Voluntary wheel-running (+EX) in heterozygous...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Danson, E, Mankia, K, Golding, S, Dawson, T, Everatt, L, Cai, S, Channon, K, Paterson, D
פורמט:	Journal article
שפה:	English
יצא לאור:	2004

פריטים דומים

Impaired regulation of neuronal nitric oxide synthase during exercise abolishes training-induced facilitation of cardiac vagal function in mice lacking one nNOS allele
מאת: Danson, E, et al.
יצא לאור: (2003)

Cardiac nitric oxide: emerging role for nNOS in regulating physiological function.
מאת: Danson, E, et al.
יצא לאור: (2005)

Targeted nNOS gene transfer into the cardiac vagus rapidly increases parasympathetic function in the pig.
מאת: Heaton, D, et al.
יצא לאור: (2005)

Neuronal Nitric Oxide Synthase (nNOS) Regulates Basal Flow in the Human Coronary Circulation In Vivo
מאת: Seddon, M, et al.
יצא לאור: (2008)

Inhibition of interferon-gamma-stimulated melanoma progression by targeting neuronal nitric oxide synthase (nNOS)
מאת: Shirley Tong, et al.
יצא לאור: (2022-02-01)

Targeting neuronal nitric oxide synthase with gene transfer to modulate cardiac autonomic function.
מאת: Mohan, R, et al.
יצא לאור: (2004)

Gene transfer of neuronal nitric oxide synthase into intracardiac Ganglia reverses vagal impairment in hypertensive rats.
מאת: Heaton, D, et al.
יצא לאור: (2007)

Assessment of tamoxifen effects on nitric oxide synthase (nNOS) in rat developing hippocampus
מאת: Tabatabaeei Parvaneh, et al.
יצא לאור: (2008-07-01)

Neuronal nitric oxide synthase gene transfer promotes cardiac vagal gain of function.
מאת: Mohan, R, et al.
יצא לאור: (2002)

Adenoviral nNOS gene transfer into the cardiac vagus increases protein expression within 9 hours and enhances vagal responsiveness in the pig
מאת: Paterson, D, et al.
יצא לאור: (2004)

Role of neuronal nitric oxide synthase (nNOS) at medulla in tachycardia induced by repeated administration of ethanol in conscious rats
מאת: Jiro Hasegawa Situmorang, et al.
יצא לאור: (2018-01-01)

Neuronal nitric oxide synthase (nnos) expression following inferior alveolar nerve injury.
מאת: Davies, S, et al.
יצא לאור: (2003)

Discordant response to exercise training in nnos knockout mice: Differential role of nNOS on exercise performance versus cardiac hypertrophy
מאת: de Bono, J, et al.
יצא לאור: (2007)

Enhanced neuronal nitric oxide synthase expression is central to cardiac vagal phenotype in exercise-trained mice.
מאת: Danson, E, et al.
יצא לאור: (2003)

The heart is an early target of anthrax lethal toxin in mice: a protective role for neuronal nitric oxide synthase (nNOS).
מאת: Mahtab Moayeri, et al.
יצא לאור: (2009-05-01)

Selective gene deletion of the neuronal nitric oxide synthase (nNOS) accelerates pathological left ventricular remodelling and functional deterioration after myocardial infarction (MI)
מאת: Dawson, D, et al.
יצא לאור: (2005)

Differential role of nNOS in heart rate regulation between rest and exercise
מאת: Adlam, D, et al.
יצא לאור: (2007)

Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.
מאת: Michelle Wehling-Henricks, et al.
יצא לאור: (2011-01-01)

Regional age-related changes in neuronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain
מאת: Guidon Gérard, et al.
יצא לאור: (2006-12-01)

Nitric oxide synthase (nNOS) gene transfer modifies venous bypass graft remodeling: effects on vascular smooth muscle cell differentiation and superoxide production.
מאת: West, N, et al.
יצא לאור: (2001)

A critical role for neuronal nitric oxide synthase in the Physiologic response to exercise
מאת: De Bono, J, et al.
יצא לאור: (2007)

Tetrahydrobiopterin (BH4), a cofactor for nNOS, restores gastric emptying and nNOS expression in female diabetic rats.
מאת: Gangula, P, et al.
יצא לאור: (2010)

Confocal Laser Scanning Microscopy on the Distribution of Neural Nitric Oxide Synthase (nNOS)-immunoreactive Nerves in the Chicken Harderian Gland
מאת: Kohzy Hiramatsu, et al.
יצא לאור: (2005-02-01)

Targeting cardiac sympatho-vagal imbalance using gene transfer of nitric oxide synthase.
מאת: Danson, E, et al.
יצא לאור: (2009)

Phenotyping of nNOS neurons in the postnatal and adult female mouse hypothalamus
מאת: Chachlaki, K, et al.
יצא לאור: (2017)

Neuronal NOS (nNOS) is expressed in human osteocytes: Multiple pathways of NO regulation?
מאת: Caballero, A, et al.
יצא לאור: (2002)

The expanding roles of neuronal nitric oxide synthase (NOS1)
מאת: Kundan Solanki, et al.
יצא לאור: (2022-07-01)

Neuronal nitric oxide synthase (NOS I) in the buffalo epididymis
מאת: E. Langella, et al.
יצא לאור: (2010-02-01)

An immunohistochemical study on the presence of nitric oxide synthase isoforms (nNOS, iNOS, eNOS) in the spinal cord and nodose ganglion of rats receiving ionising gamma radiation to their liver
מאת: Yılmaz Osman, et al.
יצא לאור: (2020-09-01)

High nitrate levels in skeletal muscle contribute to nitric oxide generation via a nitrate/nitrite reductive pathway in mice that lack the nNOS enzyme
מאת: Supranee Upanan, et al.
יצא לאור: (2024-05-01)

Effect of in vivo gene transfer of nNOS in the PVN on renal nerve discharge in rats.
מאת: Li, Y, et al.
יצא לאור: (2002)

Reduced phospholamban phosphorylation is responsible for impaired myocardial relaxation in nNOS(-/-) mice
מאת: Zhang, Y, et al.
יצא לאור: (2005)

Characteristics of colonic migrating motor complexes in neuronal NOS (nNOS) knockout mice
מאת: Nick eSpencer
יצא לאור: (2013-10-01)

Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats
מאת: Li, D, et al.
יצא לאור: (2013)

Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats.
מאת: Li, D, et al.
יצא לאור: (2013)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
מאת: Alp, N, et al.
יצא לאור: (2004)

Cardiac cholinergic NO-cGMP signaling following acute myocardial infarction and nNOS gene transfer.
מאת: Dawson, T, et al.
יצא לאור: (2008)

nNOS gene transfer to RVLM improves baroreflex function in rats with chronic heart failure.
מאת: Wang, Y, et al.
יצא לאור: (2003)

Insulin resistance in mice lacking neuronal nitric oxide synthase is related to an alpha-adrenergic mechanism
מאת: P Turini, et al.
יצא לאור: (2007-12-01)

Neonatal Mice Lacking Neuronal Nitric Oxide Synthase Are Less Vulnerable to Hypoxic–Ischemic Injury
מאת: Donna M. Ferriero, et al.
יצא לאור: (1996-02-01)