Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...

Полное описание

Библиографические подробности
Главные авторы:	Liu, Y, Hu, Z, Cheng, J, Siejka-Zielinska, P, Chen, J, Inoue, M, Ahmed, A, Song, C
Формат:	Journal article
Язык:	English
Опубликовано:	Springer Nature 2021

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