Structural and functional studies of perforin-like proteins implicated in zoonotic parasitic diseases

<p>MACPF/CDCs are an ancient superfamily of pore forming proteins that have evolved a critical role in both cellular defence and attack. Many copies of MACPF/CDC proteins are released by a cell before binding to target membranes, oligomerising and undergoing a large structural rearrangement to...

Полное описание

Библиографические подробности
Главный автор: Williams, S
Другие авторы: Stansfeld, P
Формат: Диссертация
Язык:English
Опубликовано: 2019
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