1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
CAMPATH-1 antibodies have a long and successful history in the treatment of leukaemia, autoimmune disease and transplant rejection. The first antibody to undergo "humanisation", CAMPATH-1H, permits treatment with limited patient anti-globulin response. It recognises the CD52 antigen which...
Autori principali: | James, L, Hale, G, Waldmann, H, Bloomer, A, Waldman, H |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1999
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