Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.

Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.

The effects of the APOE epsilon4 allele on a range of pre- and postsynaptic cholinergic markers were studied in a cohort of community-based Alzheimer's disease (AD) patients. Compared with age-matched controls, the postmortem AD neocortex showed decreased choline acetyltransferase (ChAT) and ac...

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Detalhes bibliográficos
Main Authors:	Lai, M, Tsang, S, Garcia-Alloza, M, Minger, S, Nicoll, J, Esiri, M, Wong, P, Chen, C, Ramírez, M, Francis, P
Formato:	Journal article
Idioma:	English
Publicado em:	2006

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