Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.
The effects of the APOE epsilon4 allele on a range of pre- and postsynaptic cholinergic markers were studied in a cohort of community-based Alzheimer's disease (AD) patients. Compared with age-matched controls, the postmortem AD neocortex showed decreased choline acetyltransferase (ChAT) and ac...
Những tác giả chính: | Lai, M, Tsang, S, Garcia-Alloza, M, Minger, S, Nicoll, J, Esiri, M, Wong, P, Chen, C, Ramírez, M, Francis, P |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2006
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