Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.

Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.

Chromosomal DNA replication requires one daughter strand-the lagging strand-to be synthesised as a series of discontinuous, RNA-primed Okazaki fragments, which must subsequently be matured into a single covalent DNA strand. Here, we describe the reconstitution of Okazaki fragment maturation in vitro...

书目详细资料
Main Authors:	Beattie, T, Bell, S
格式:	Journal article
语言:	English
出版:	2012

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