Resolution of lambda/10 in fluorescence microscopy using fast single molecule photo-switching

We demonstrate nanoscale resolution in far-field optical microscopy based on photo-switching of molecules. By enabling, recording and disabling fluorescence from individual labels sequentially, the detection volume is reduced to the size of a single molecule and the diffraction limit is broken. Imag...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Geisler, C, Schoenle, A, von Middendorff, C, Bock, H, Eggeling, C, Egner, A, Hell, S
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2007