Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

Cyclin-Dependent Kinase 12 (CDK12), Human Kinase Domain; A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its l...

Detaylı Bibliyografya
Diğer Yazarlar:	Bullock, A
Materyal Türü:	Dataset
Baskı/Yayın Bilgisi:	University of Oxford 2018
Konular:	Chemical Biology Structural Genomics Drug Discovery

Benzer Materyaller

Cyclin-dependent kinase 12 (CDK12), human kinase domain; a Target Enabling Package
Yazar:: Dixon-Clarke, S
Baskı/Yayın Bilgisi: (2018)

Cyclin-Dependent Kinase 12 (CDK12), human kinase domain; A Target Enabling Package
Baskı/Yayın Bilgisi: (2018)

LIM domain kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
Yazar:: Mathea, S
Baskı/Yayın Bilgisi: (2018)

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
Yazar:: Bullock, A
Baskı/Yayın Bilgisi: (2018)

LIM Domain Kinase 1 (LIMK1), human kinase domain; A Target Enabling Package
Yazar:: Mathea, S
Baskı/Yayın Bilgisi: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
Yazar:: Bullock, A
Baskı/Yayın Bilgisi: (2018)

With no lysine kinase 3 (WNK3); A Target Enabling Package
Yazar:: Pinkas, D
Baskı/Yayın Bilgisi: (2018)

With No Lysine Kinase 3 (WNK3); A Target Enabling Package
Yazar:: Pinkas, D
Baskı/Yayın Bilgisi: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
Yazar:: Cox, O
Baskı/Yayın Bilgisi: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
Yazar:: Cox, O
Baskı/Yayın Bilgisi: (2018)

Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package
Yazar:: Brennan, P
Baskı/Yayın Bilgisi: (2018)

Human RECQL5 Helicase; A Target Enabling Package
Yazar:: Gileadi, O
Baskı/Yayın Bilgisi: (2018)

Human RECQL5 Helicase; A Target Enabling Package
Yazar:: Newman, J
Baskı/Yayın Bilgisi: (2018)

Human RECQL5 Helicase; A Target Enabling Package
Yazar:: Newman, J
Baskı/Yayın Bilgisi: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Baskı/Yayın Bilgisi: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Yazar:: Kopec, J
Baskı/Yayın Bilgisi: (2018)

Human alpha-aminoadipic semialdehyde synthase (AASS); A Target Enabling Package
Yazar:: Yue, W
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
Yazar:: Brennan, P
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
Yazar:: Brennan, P
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
Yazar:: Savitsky, P
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
Yazar:: Brennan, P
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD2D (KDM4D); A Targeting Enabling Package
Yazar:: Brennan, P
Baskı/Yayın Bilgisi: (2018)

Lysine Demethylase JMJD1B (KDM3B); A Target Enabling Package
Yazar:: Savitsky, P
Baskı/Yayın Bilgisi: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
Yazar:: Carpenter, E
Baskı/Yayın Bilgisi: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
Yazar:: Chu, A
Baskı/Yayın Bilgisi: (2018)

Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (DPAGT1); A Target Enabling Package
Yazar:: Dong, Y
Baskı/Yayın Bilgisi: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
Yazar:: Newman, J
Baskı/Yayın Bilgisi: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
Yazar:: Gileadi, O
Baskı/Yayın Bilgisi: (2018)

Human DNA Cross-Link Repair 1A (DCLRE1A, SNM1A); A Target Enabling Package
Yazar:: Newman, J
Baskı/Yayın Bilgisi: (2018)

Meiotic regulation of cyclin-dependent kinases
Yazar:: Miller, Matthew P., Ph. D. (Matthew Paul). Massachusetts Institute of Technology
Baskı/Yayın Bilgisi: (2013)

Identification and Functional Characterisation of CRK12:CYC9, a Novel Cyclin-Dependent Kinase (CDK)-Cyclin Complex in Trypanosoma brucei.
Yazar:: Séverine Monnerat, ve diğerleri
Baskı/Yayın Bilgisi: (2013-01-01)

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning
Yazar:: Gabriella O Estevam, ve diğerleri
Baskı/Yayın Bilgisi: (2025-02-01)

Cyclin-dependent kinase (CDK) 4/6 inhibitors in oncology
Yazar:: Karamitrousis Evangelos, ve diğerleri
Baskı/Yayın Bilgisi: (2020-04-01)

Cyclin-dependent kinases and CDK inhibitors in virus-associated cancers
Yazar:: Shaian Tavakolian, ve diğerleri
Baskı/Yayın Bilgisi: (2020-05-01)

Cyclin-Dependent Kinase regulation and function during meiosis
Yazar:: Carlile, Thomas M. (Thomas Marshal), Jr
Baskı/Yayın Bilgisi: (2010)

Cyclin‐dependent kinase 12‐mediated super‐enhancers as promising targets in cancer therapy
Yazar:: Fuda Xie, ve diğerleri
Baskı/Yayın Bilgisi: (2022-12-01)

Functional characterization of the cyclin-dependent kinase inhibitor p21 by gene targeting in the mouse
Yazar:: Brugarolas, James (James Burfau), 1969-
Baskı/Yayın Bilgisi: (2009)

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
Yazar:: Andrea Brenna, ve diğerleri
Baskı/Yayın Bilgisi: (2019-11-01)

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine
Yazar:: Moustapha Hassan, ve diğerleri
Baskı/Yayın Bilgisi: (2011-08-01)

Cyclin K goes with Cdk12 and Cdk13
Yazar:: Kohoutek Jiri, ve diğerleri
Baskı/Yayın Bilgisi: (2012-04-01)