Induction and repair of clustered DNA lesions: what do we know so far?

The accumulated evidence in the literature indicates that a cluster of two or more lesions within one or two helical turns of the DNA is more challenging to repair than individual, widely dispersed lesions. The biological importance of clustered DNA lesions, especially complex double-strand breaks (...

全面介紹

書目詳細資料
Main Authors: Georgakilas, A, O'Neill, P, Stewart, R
格式: Journal article
語言:English
出版: 2013