Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site.
Hepatitis A virus (HAV) infects ∼1.4 million people annually and, although there is a vaccine, there are no licensed therapeutic drugs. HAV is unusually stable (making disinfection problematic) and little is known of how it enters cells and releases its RNA. Here we report a potent HAV-specific mono...
Главные авторы: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Kotecha, A, Walter, T, Wang, J, Fry, E, Stuart, D, Rao, Z |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
National Academy of Sciences
2017
|
Схожие документы
-
Neutralization mechanisms of two highly potent antibodies against human enterovirus 71
по: Zhu, L, и др.
Опубликовано: (2018) -
Neutralization mechanisms of two highly potent antibodies against human enterovirus 71
по: Zhu, L, и др.
Опубликовано: (2018) -
Structure of human Aichi virus and implications for receptor binding
по: Zhu, L, и др.
Опубликовано: (2016) -
Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2
по: Zhou, D, и др.
Опубликовано: (2018) -
Electrochemical recognition of charged and neutral guest species by redox-active receptor molecules
по: Beer, P, и др.
Опубликовано: (1998)