Structural insights into diverse modes of ICAM-1 binding by Plasmodium falciparum-infected erythrocytes
A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected individuals. This occludes blood flow, leads to inflammation, and increases parasitemia by reducing spleen-mediated clearance of...
المؤلفون الرئيسيون: | Lennartz, F, Smith, C, Craig, A, Higgins, M |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
National Academy of Sciences
2019
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مواد مشابهة
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Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1.
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منشور في: (2018) -
The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site.
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منشور في: (2008) -
Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding
حسب: Lennartz, F, وآخرون
منشور في: (2015)