Dynamic regulation of CD28 conformation and signaling by charged lipids and ions

CD28 provides an essential co-stimulatory signal for T cell activation and its function is critical in antitumor immunity. However, the molecular mechanism of CD28 transmembrane signaling remains elusive. Here, we find that CD28 conformation and signaling are regulated by two counteractive charge...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Yang, W, Pan, W, Chen, S, Trendel, N, Jiang, S, Xiao, F, Xue, M, Wu, W, Peng, Z, Li, X, Ji, H, Liu, X, Jiang, H, Wang, H, Shen, H, Dushek, O, Li, H, Xu, C
Μορφή:	Journal article
Έκδοση:	Springer Nature 2017

Dynamic regulation of CD28 conformation and signaling by charged lipids and ions

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