From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.

The regulation of blood red cell production by the hormone erythropoietin (Epo) provides a paradigm for control of gene expression by oxygen. Analysis of this pathway has revealed a widespread system of gene regulation based on a transcriptional complex termed hypoxia-inducible factor (HIF). Hydroxy...

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Hoofdauteur:	Ratcliffe, P
Formaat:	Conference item
Gepubliceerd in:	2002

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