Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas.
Several single-nucleotide polymorphisms (SNPs) have been associated with colorectal cancer (CRC) susceptibility. Most CRCs arise from adenomas, and SNPs therefore might affect predisposition to CRC by increasing adenoma risk. We found that 8 of 18 known CRC-associated SNPs (rs10936599, rs6983267, rs...
Автори: | Carvajal-Carmona, L, Zauber, A, Jones, A, Howarth, K, Wang, J, Cheng, T, Riddell, R, Lanas, A, Morton, D, Bertagnolli, M, Tomlinson, I |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2013
|
Схожі ресурси
Схожі ресурси
-
TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres
за авторством: Jones, A, та інші
Опубліковано: (2012) -
TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres.
за авторством: Jones, A, та інші
Опубліковано: (2012) -
Genetic Variants Associated with Colorectal Adenoma Susceptibility.
за авторством: Anna Abulí, та інші
Опубліковано: (2016-01-01) -
Homozygous PMS2 deletion causes a severe colorectal cancer and multiple adenoma phenotype without extraintestinal cancer.
за авторством: Will, O, та інші
Опубліковано: (2007) -
Fine Mapping of Colorectal Cancer Low Penetrance Susceptibility Loci
за авторством: Carvajal-Carmona, L, та інші
Опубліковано: (2009)