Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.

Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes.

The exposure of human T-cell clones to supra-immunogenic concentrations of peptide antigen in the absence of accessory cells induces antigen-specific unresponsiveness. Using this model we have investigated the ability of cytokines to modulate the induction of, or reversal of, T-cell tolerance. Our f...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Essery, G, Feldmann, M, Lamb, JR
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1988

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