Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.
MicroRNAs are important regulators of gene expression, yet the functional outputs of most microRNA-target interactions remain elusive. Here we introduce the Drosophila melanogaster microRNA sponge (miR-SP) as a powerful transgenic technology to dissect the function of every microRNA with precise spa...
Hauptverfasser: | , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2009
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