In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.

The LKB1/STK11 serine/threonine kinase is mutated in Peutz-Jeghers' syndrome and acts as a tumour suppressor. Using northern blotting and RT-PCR, LKB1 has been reported to be expressed widely in human adult tissues, although in Xenopus the expression of its homologue, XEEK1, is apparently restr...

ver descrição completa

Detalhes bibliográficos
Main Authors: Rowan, A, Churchman, M, Jefferey, R, Hanby, A, Poulsom, R, Tomlinson, I
Formato: Journal article
Idioma:English
Publicado em: 2000