Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.

An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoac...

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Autori principali: Claridge, T, Davies, S, Lee, J, Nicholson, R, Roberts, P, Russell, A, Smith, A, Toms, S
Natura: Journal article
Lingua:English
Pubblicazione: 2008