Relationship of NAD(P)H oxidase activity in human blood vessels to endothelial dysfunction and clinical risk factors

Relationship of NAD(P)H oxidase activity in human blood vessels to endothelial dysfunction and clinical risk factors

Vascular superoxide production is increased in animal models of atherosclerosis, diabetes and hypertension, and reduces nitric oxide (NO) bioactivity. However, the functional importance of superoxide production in human atherosclerosis is poorly characterised. We aimed to determine the relationships...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Guzik, T, West, N, Black, E, McDonald, D, Ratnatunga, C, Pillai, R, Channon, K
Format:	Journal article
Sprog:	English
Udgivet:	2000

Lignende værker

Association of superoxide production by NAD(P)H oxidase with systaemic endothelial dysfunction in human blood vessels: relationship to clinical risk factors
af: Guzik, T, et al.
Udgivet: (2000)

Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors.
af: Guzik, T, et al.
Udgivet: (2000)

Superoxide production by NAD(P)H oxidase in human blood vessels: Functional interaction with nitric oxide
af: Guzik, T, et al.
Udgivet: (2000)

UltraRapid communications : vascular superoxide production by NAD(P)H OxidaseAssociation with endothelial dysfunction and clinical risk factors
af: Guzik, T, et al.
Udgivet: (2000)

Superoxide generation by NAD(P)H oxidase in human sphenous vein: Interaction with nitric oxide
af: Guzik, T, et al.
Udgivet: (2000)

Functional impact of genetic polymorphisms in NAD(P)H oxidase p22phox subunit on vascular superoxide production in atherosclerosis
af: Guzik, T, et al.
Udgivet: (2000)

Systemic upregulation of vascular NAD(P)H oxidase in human atherosclerosis: Association with clinical risk factors.
af: Guzik, T, et al.
Udgivet: (2000)

Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis.
af: Guzik, T, et al.
Udgivet: (2000)

Functional importance of C242T polymorphism in NAD(P)H oxidase p22phox subunit on vascular superoxide production in atherosclerosis
af: Guzik, T, et al.
Udgivet: (2000)

Enhanced superoxide anion production in experimental venous bypass grafts is mediated by NAD(P)H oxidase
af: West, N, et al.
Udgivet: (2000)

Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase.
af: Guzik, T, et al.
Udgivet: (2002)

Vascular superoxide generation by NAD(P)H oxidase is increased in humans with type II diabetes mellitus
af: Guzik, T, et al.
Udgivet: (2001)

Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase and nitric oxide-mediated endothelial function in human atherosclerosis.
af: Guzik, T, et al.
Udgivet: (2001)

Superoxide generation by NAD(P)H oxidases in human bypass graft vessels.
af: Guzik, T, et al.
Udgivet: (2002)

Relationships of promoter and coding sequence genetic polymorphisms of p22phox subunit to the vascular NAD(P)H oxidase activity
af: Guzik, T, et al.
Udgivet: (2004)

Enhanced superoxide production in experimental venous bypass graft intimal hyperplasia: role of NAD(P)H oxidase.
af: West, N, et al.
Udgivet: (2001)

Mechanisms of superoxide production in human blood vessels: relationship to endothelial dysfunction, clinical and genetic risk factors.
af: Channon, K, et al.
Udgivet: (2002)

A myocardial nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation (AF)
af: Kim, Y, et al.
Udgivet: (2003)

A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation
af: Kim, Y, et al.
Udgivet: (2005)

A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation.
af: Kim, Y, et al.
Udgivet: (2005)

Superoxide production by NAD(P)H oxidases in human bypass graft vessels - Role in the regulation of vascular tone
af: Guzik, T, et al.
Udgivet: (2002)

Atrial NAD(P)H oxidase activity predicts the development of atrial fibrillation after coronary artery bypass graft surgery
af: Kim, Y, et al.
Udgivet: (2006)

Atrial NAD(P)H oxidase activity predicts the development of atrial fibrillation after on-pump coronary artery bypass graft surgery
af: Kim, Y, et al.
Udgivet: (2005)

Superoxide generation during cardiopulmonary bypass in conventional coronary artery bypass graft surgery: is there a role for myocardial NAD(P)H oxidase?
af: Kim, Y, et al.
Udgivet: (2004)

A myocardial nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation
af: Kim, Y, et al.
Udgivet: (2005)

Minimally invasive saphenous vein harvesting: effects on endothelial and smooth muscle function.
af: Black, E, et al.
Udgivet: (2001)

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins
af: Guzik, T, et al.
Udgivet: (2004)

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.
af: Guzik, T, et al.
Udgivet: (2004)

Endothelial and smooth muscle function are preserved with minimally invasive saphenous vein harvest: A prospective randomised trial.
af: Black, E, et al.
Udgivet: (2000)

Increased NAD(P)H oxidase activity in coronary arteries from patients with coronary artery disease
af: Guzik, T, et al.
Udgivet: (2001)

Nitric oxide-superoxide interactions in human blood vessels: implications for vascular peroxynitrite formation
af: Guzik, T, et al.
Udgivet: (2001)

Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels.
af: Guzik, T, et al.
Udgivet: (2002)

Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.
af: Sachin Gupte, et al.
Udgivet: (2010-07-01)

Direct improvement of endothelial function and superoxide production in human vessels, by oral folic acid treatment: A double blind placebo controlled study
af: Antoniades, C, et al.
Udgivet: (2005)

5-methyl-tetrahydrofolate acid improves endothelial function and decreases superoxide production in vessels from patients with coronary artery disease
af: Antoniades, C, et al.
Udgivet: (2006)

Endothelial dysfunction and increased vascular superoxide generation in the type II diabetic (Goto-Kakisaki) rat occur independently of plasma cholesterol levels
af: West, N, et al.
Udgivet: (2000)

Low- and high- dose treatment with folic acid, equally improve endothelial function and decrease superoxide production in human vessels via tetrahydrobiopterin-mediated eNOS coupling
af: Antoniades, C, et al.
Udgivet: (2007)

Chronic treatment with folic acid improves endothelial function and decreases superoxide production in human vessels. A double blind placebo control study
af: Shirodaria, C, et al.
Udgivet: (2005)

TARGETING NOX2 NADPH OXIDASE IN INSULIN RESISTANCE RELATED ENDOTHELIAL DYSFUNCTION
af: Sukumar, P, et al.
Udgivet: (2013)

TARGETING NOX2 NADPH OXIDASE IN INSULIN RESISTANCE RELATED ENDOTHELIAL DYSFUNCTION
af: Sukumar, P, et al.
Udgivet: (2013)