Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

To this day, a significant proportion of the human genome remains devoid of functional characterization. In this study, we present evidence that the previously functionally uncharacterized product of the human DHRS10 gene is endowed with 17beta-HSD (17beta-hydroxysteroid dehydrogenase) activity. 17b...

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Autors principals: Lukacik, P, Keller, B, Bunkoczi, G, Kavanagh, K, Lee, W, Adamski, J, Oppermann, U
Format: Journal article
Idioma:English
Publicat: 2007
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