Asymmetric synthesis of d-fagomine and its diastereoisomers

Asymmetric synthesis of d-fagomine and its diastereoisomers

A divergent strategy for the asymmetric syntheses of d-fagomine and three of its diastereoisomers has been developed. The diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester was used as the key step to install the correct configuration required for the C...

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Detalhes bibliográficos
Principais autores:	Davies, S, Fletcher, A, Kennedy, M, Roberts, P, Thomson, J
Formato:	Journal article
Publicado em:	Elsevier 2018

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