Asymmetric synthesis of d-fagomine and its diastereoisomers

A divergent strategy for the asymmetric syntheses of d-fagomine and three of its diastereoisomers has been developed. The diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester was used as the key step to install the correct configuration required for the C...

Полное описание

Библиографические подробности
Главные авторы: Davies, S, Fletcher, A, Kennedy, M, Roberts, P, Thomson, J
Формат: Journal article
Опубликовано: Elsevier 2018