Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets.

BACKGROUND: Influenza A viruses generate an extreme genetic diversity through point mutation and gene segment exchange, resulting in many new strains that emerge from the animal reservoirs, among which was the recent highly pathogenic H5N1 virus. This genetic diversity also endows these viruses wit...

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Autori principali: Heiny, A, Miotto, O, Srinivasan, K, Khan, A, Zhang, G, Brusic, V, Tan, T, August, J
Natura: Journal article
Lingua:English
Pubblicazione: Public Library of Science 2007

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