Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy.
BACKGROUND: Human female meiosis is particularly error prone, leading to the generation of aneuploidy, a problem which increases dramatically with advancing age. Despite being of great clinical importance, the genesis of oocyte aneuploidy remains poorly understood. Cumulus cells (CCs) surround oocy...
Main Authors: | Fragouli, E, Wells, D, Iager, A, Kayisli, U, Patrizio, P |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2012
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Lignende værker
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TRANCRIPTOMIC PROFILING OF CUMULUS CELLS FROM NORMAL AND ANEUPLOID OOCYTES: TOWARDS A NON-INVASIVE DIAGNOSIS OF MEIOTIC ANEUPLOIDY
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Follicle-specific predisposition to aneuploidy as revealed by transcriptomic analysis of cumulus cells
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Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression.
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