Development of a sensitive, scalable method for spatial, cell-type-resolved proteomics of the human brain

Development of a sensitive, scalable method for spatial, cell-type-resolved proteomics of the human brain

While nearly comprehensive proteome coverage can be achieved from bulk tissue or cultured cells, the data usually lacks spatial resolution. As a result, tissue based proteomics averages protein abundance across multiple cell types and/or localizations. With proteomics platforms lacking sensitivity a...

書誌詳細
主要な著者:	Davis, S, Scott, C, Ansorge, O, Fischer, R
フォーマット:	Journal article
言語:	English
出版事項:	American Chemical Society 2019

類似資料

Spatially resolved proteomics of a human brain tumour
著者:: Davis, S
出版事項: (2021)

Deep topographic proteomics of a human brain tumour
著者:: Davis, S, 等
出版事項: (2023)

Multiplexed, scalable, and functionality compatible platforms for 3D spatially resolved proteomic profiling
著者:: Tian, Yuxuan
出版事項: (2024)

Deep topographic proteomics of a human brain tumour
著者:: Simon Davis, 等
出版事項: (2023-11-01)

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin
著者:: Beatrice Dyring-Andersen, 等
出版事項: (2020-11-01)

Spatially resolved proteomics via tissue expansion
著者:: Lu Li, 等
出版事項: (2022-11-01)

Region and cell-type resolved quantitative proteomic map of the human heart
著者:: Sophia Doll, 等
出版事項: (2017-11-01)

Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms
著者:: Ruth S. Nelson, 等
出版事項: (2022-06-01)

Spatially resolved mapping of proteome turnover dynamics with subcellular precision
著者:: Feng Yuan, 等
出版事項: (2023-11-01)

Spatially-resolved proteomics and transcriptomics: An emerging digital spatial profiling approach for tumor microenvironment
著者:: Wang Nan, 等
出版事項: (2021-01-01)

A region-resolved mucosa proteome of the human stomach
著者:: Xiaotian Ni, 等
出版事項: (2019-01-01)

Dissecting the brain with spatially resolved multi-omics
著者:: Yijia Fangma, 等
出版事項: (2023-07-01)

Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment
著者:: Lenora Higginbotham, 等
出版事項: (2023-10-01)

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
著者:: Anoushka Joglekar, 等
出版事項: (2021-01-01)

Proteomics and transcriptomics of the Betz cell in the human brain
著者:: Scott, C
出版事項: (2021)

Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2
著者:: Hung, Victoria, 等
出版事項: (2016)

Multimodal single cell-resolved spatial proteomics reveal pancreatic tumor heterogeneity
著者:: Yanfen Xu, 等
出版事項: (2024-11-01)

Spatially resolved proteomic map shows that extracellular matrix regulates epidermal growth
著者:: Jun Li, 等
出版事項: (2022-07-01)

Spatially resolved proteomics identify biomarkers from endometrial sentinel lymph nodes
著者:: Renliang Li, 等
出版事項: (2021-06-01)

Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain
著者:: Sruti Rayaprolu, 等
出版事項: (2022-05-01)

Scalable Subcellular Resolution Mapping of the Human Brain
著者:: Guan, Webster
出版事項: (2023)

New chemical biopsy tool for spatially resolved profiling of human brain tissue in vivo
著者:: Joanna Bogusiewicz, 等
出版事項: (2021-09-01)

Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome
著者:: Fu Zheng, 等
出版事項: (2023-05-01)

83 Spatially resolved transcriptomic and proteomic investigation of breast cancer and its immune microenvironment
著者:: Stephen Williams, 等
出版事項: (2021-11-01)

Spatial-ID: a cell typing method for spatially resolved transcriptomics via transfer learning and spatial embedding
著者:: Rongbo Shen, 等
出版事項: (2022-12-01)

High-sensitive spatially resolved T cell receptor sequencing with SPTCR-seq
著者:: Jasim Kada Benotmane, 等
出版事項: (2023-11-01)

Spatially and spectrally resolved multicore optical fiber sensor with polarization sensitivity
著者:: Y. Hou, 等
出版事項: (2022-06-01)

Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury
著者:: Ling Leng, 等
出版事項: (2022-06-01)

Spatially resolved analysis of Pseudomonas aeruginosa biofilm proteomes measured by laser ablation sample transfer.
著者:: Aruni Chathurya Pulukkody, 等
出版事項: (2021-01-01)

The proteome of human brain microdialysate
著者:: Feldmann Robert E, 等
出版事項: (2003-12-01)

A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
著者:: Mfon E Umoh, 等
出版事項: (2017-11-01)

SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data.
著者:: Souvik Seal, 等
出版事項: (2023-10-01)

Publisher Correction: Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome
著者:: Fu Zheng, 等
出版事項: (2023-08-01)

Spatially and temporally resolved metabolome of the human oral cavity
著者:: Alessio Ciurli, 等
出版事項: (2024-02-01)

Using Temporally and Spatially Resolved Measurements to Improve the Sensitivity of Fluorescence-Based Immunoassays
著者:: Ran Kremer, 等
出版事項: (2024-04-01)

Representative proteomes: a stable, scalable and unbiased proteome set for sequence analysis and functional annotation.
著者:: Chuming Chen, 等
出版事項: (2011-04-01)

Capillary Electrophoresis Mass Spectrometry for Scalable Single-Cell Proteomics
著者:: Bowen Shen, 等
出版事項: (2022-04-01)

A highly scalable peptide-based assay system for proteomics.
著者:: Igor A Kozlov, 等
出版事項: (2012-01-01)

Scalable Delay-Sensitive Polling of Sensors
著者:: Hootan Rashtian, 等
出版事項: (2020-01-01)

Scalable mapping of myelin and neuron density in the human brain with micrometer resolution
著者:: Shuaibin Chang, 等
出版事項: (2022-01-01)