Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing
Necrotising fasciitis (NF) is a rare manifestation of invasive Streptococcus pyogenes (GAS) infection associated with a substantial risk of death or disability. Hypothesising that host genetic factors might contribute, we sought to identify rare deleterious variants contributing to NF susceptibility...
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| Formáid: | Conference item |
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European Society of Clinical Microbiology and Infectious Disease
2018
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| _version_ | 1826302775310417920 |
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| author | Parks, T Elliott, K Lamagni, T Malinauskas, T Murphy, M Petherbridge, L Guy, R Auckland, K Mentzer, A Marsden, D Strakova, L Chapman, S Hill, A Sriskandan, S Knight, J |
| author_facet | Parks, T Elliott, K Lamagni, T Malinauskas, T Murphy, M Petherbridge, L Guy, R Auckland, K Mentzer, A Marsden, D Strakova, L Chapman, S Hill, A Sriskandan, S Knight, J |
| author_sort | Parks, T |
| collection | OXFORD |
| description | Necrotising fasciitis (NF) is a rare manifestation of invasive Streptococcus pyogenes (GAS) infection associated with a substantial risk of death or disability. Hypothesising that host genetic factors might contribute, we sought to identify rare deleterious variants contributing to NF susceptibility. |
| first_indexed | 2024-03-07T05:52:36Z |
| format | Conference item |
| id | oxford-uuid:e96741c7-2084-4ba0-8589-a37381d38e5e |
| institution | University of Oxford |
| last_indexed | 2024-03-07T05:52:36Z |
| publishDate | 2018 |
| publisher | European Society of Clinical Microbiology and Infectious Disease |
| record_format | dspace |
| spelling | oxford-uuid:e96741c7-2084-4ba0-8589-a37381d38e5e2022-03-27T10:54:03ZRare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencingConference itemhttp://purl.org/coar/resource_type/c_c94fuuid:e96741c7-2084-4ba0-8589-a37381d38e5eSymplectic Elements at OxfordEuropean Society of Clinical Microbiology and Infectious Disease2018Parks, TElliott, KLamagni, TMalinauskas, TMurphy, MPetherbridge, LGuy, RAuckland, KMentzer, AMarsden, DStrakova, LChapman, SHill, ASriskandan, SKnight, JNecrotising fasciitis (NF) is a rare manifestation of invasive Streptococcus pyogenes (GAS) infection associated with a substantial risk of death or disability. Hypothesising that host genetic factors might contribute, we sought to identify rare deleterious variants contributing to NF susceptibility. |
| spellingShingle | Parks, T Elliott, K Lamagni, T Malinauskas, T Murphy, M Petherbridge, L Guy, R Auckland, K Mentzer, A Marsden, D Strakova, L Chapman, S Hill, A Sriskandan, S Knight, J Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title | Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title_full | Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title_fullStr | Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title_full_unstemmed | Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title_short | Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing |
| title_sort | rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group a streptococcal necrotising fasciitis by whole exome sequencing |
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