Assessment of repurposed compounds against coronaviruses highlights the antiviral broad-spectrum activity of host-targeting iminosugars and confirms the activity of potent directly acting antivirals

Assessment of repurposed compounds against coronaviruses highlights the antiviral broad-spectrum activity of host-targeting iminosugars and confirms the activity of potent directly acting antivirals

The COVID-19 pandemic highlights the need for novel antiviral drug discovery approaches that could dramatically shorten timelines from compound discovery to clinical development. At the beginning of the pandemic, repurposing approaches were at the forefront of early research efforts to screen for an...

Полное описание

Библиографические подробности
Главные авторы:	Brun, J, Arman, BY, Hill, ML, Kiappes, JL, Alonzi, DS, Makower, LL, Witt, KD, Gileadi, C, Rangel, V, Dwek, RA, Von Delft, A, Zitzmann, N
Формат:	Journal article
Язык:	English
Опубликовано:	Elsevier 2025

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