The rise and fall of NMDA antagonists for ischemic stroke.
It has long been accepted that high concentrations of glutamate can destroy neurons, and this is the basis of the theory of excitotoxicity during brain injury such as stroke. Glutamate N-methyl-D-aspartate (NMDA) receptor antagonists such as Selfotel, Aptiganel, Gavestinel and others failed to show...
Hlavní autoři: | Hoyte, L, Barber, P, Buchan, A, Hill, MD |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2004
|
Podobné jednotky
-
NMDA antagonists: their role in neuroprotection.
Autor: Small, D, a další
Vydáno: (1997) -
NMDA antagonists: their role in neuroprotection.
Autor: Small, D, a další
Vydáno: (1997) -
Do NMDA antagonists prevent neuronal injury? No.
Autor: Buchan, A
Vydáno: (1992) -
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
Autor: Buchan, A, a další
Vydáno: (1993) -
The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke.
Autor: Buchan, A, a další
Vydáno: (1992)