The rise and fall of NMDA antagonists for ischemic stroke.
It has long been accepted that high concentrations of glutamate can destroy neurons, and this is the basis of the theory of excitotoxicity during brain injury such as stroke. Glutamate N-methyl-D-aspartate (NMDA) receptor antagonists such as Selfotel, Aptiganel, Gavestinel and others failed to show...
主要な著者: | Hoyte, L, Barber, P, Buchan, A, Hill, MD |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2004
|
類似資料
類似資料
-
NMDA antagonists: their role in neuroprotection.
著者:: Small, D, 等
出版事項: (1997) -
NMDA antagonists: their role in neuroprotection.
著者:: Small, D, 等
出版事項: (1997) -
Do NMDA antagonists prevent neuronal injury? No.
著者:: Buchan, A
出版事項: (1992) -
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
著者:: Buchan, A, 等
出版事項: (1993) -
The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke.
著者:: Buchan, A, 等
出版事項: (1992)