Weighing-up protein dynamics: the combination of native mass spectrometry and molecular dynamics simulations

Structural dynamics underpin biological function at the molecular level, yet many biophysical and structural biology approaches give only a static or averaged view of proteins. Native mass spectrometry yields spectra of the many states and interactions in the structural ensemble, but its spatial res...

Полное описание

Библиографические подробности
Главные авторы: Marklund, E, Benesch, J
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2019