Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.

In response to DNA damage, eukaryotic cells must rapidly load DNA repair proteins onto damaged chromatin. Chromatin recruitment often entails ubiquitination of a damage-specific DNA repair protein, interaction with a ubiquitin binding factor, assembly of a multisubunit DNA repair complex, and eventu...

ver descrição completa

Detalhes bibliográficos
Main Authors: Cohn, M, D'Andrea, A
Formato: Journal article
Idioma:English
Publicado em: 2008