Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.
In response to DNA damage, eukaryotic cells must rapidly load DNA repair proteins onto damaged chromatin. Chromatin recruitment often entails ubiquitination of a damage-specific DNA repair protein, interaction with a ubiquitin binding factor, assembly of a multisubunit DNA repair complex, and eventu...
Huvudupphovsmän: | , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2008
|