The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.

CD1d-restricted lymphocytes recognize a broad lipid range. However, how CD1d-restricted lymphocytes translate T cell receptor (TCR) recognition of lipids with similar group heads into distinct biological responses remains unclear. Using a soluble invariant NKT (iNKT) TCR and a newly engineered antib...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	McCarthy, C, Shepherd, D, Fleire, S, Stronge, V, Koch, M, Illarionov, P, Bossi, G, Salio, M, Denkberg, G, Reddington, F, Tarlton, A, Reddy, BG, Schmidt, R, Reiter, Y, Griffiths, G, Van Der Merwe, P, Besra, G, Jones, E, Batista, F, Cerundolo, V
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2007

Παρόμοια τεκμήρια

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation
ανά: Veerapen, N, κ.ά.
Έκδοση: (2011)

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation.
ανά: Veerapen, N, κ.ά.
Έκδοση: (2011)

Harnessing NKT cells for therapeutic applications.
ανά: Cerundolo, V, κ.ά.
Έκδοση: (2007)

A closer look at CD1d molecules: new horizons in studying NKT cells.
ανά: Stronge, V, κ.ά.
Έκδοση: (2007)

Nonglycosidic agonists of invariant NKT cells for use as vaccine adjuvants.
ανά: Reddy, BG, κ.ά.
Έκδοση: (2009)

Essential role for autophagy during invariant NKT cell development
ανά: Salio, M, κ.ά.
Έκδοση: (2014)

Harnessing invariant NKT cells in vaccination strategies.
ανά: Cerundolo, V, κ.ά.
Έκδοση: (2009)

Invariant NKT Cell at the Interface between Innate and Adaptive Immunity
ανά: Salio, M, κ.ά.
Έκδοση: (2011)

Nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells
ανά: Silk, J, κ.ά.
Έκδοση: (2008)

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.
ανά: Barral, P, κ.ά.
Έκδοση: (2008)

Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells.
ανά: Silk, J, κ.ά.
Έκδοση: (2008)

NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology.
ανά: J Christoph Vahl, κ.ά.
Έκδοση: (2013-01-01)

Non-glycosidic compounds can stimulate both human and mouse iNKT cells.
ανά: Jukes, J, κ.ά.
Έκδοση: (2016)

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
ανά: Rebeca Jimeno, κ.ά.
Έκδοση: (2019-12-01)

Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d molecules.
ανά: Denkberg, G, κ.ά.
Έκδοση: (2008)

Amide analogues of CD1d agonists modulate iNKT-cell-mediated cytokine production.
ανά: Wojno, J, κ.ά.
Έκδοση: (2012)

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
ανά: Rebeca Jimeno, κ.ά.
Έκδοση: (2020-03-01)

Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells.
ανά: Hermans, I, κ.ά.
Έκδοση: (2007)

Expansion of highly activated iNKT cells with altered phenotype in acute dengue infection.
ανά: Kamaladasa, A, κ.ά.
Έκδοση: (2016)

The role of invariant NKT cells at the interface of innate and adaptive immunity
ανά: Cerundolo, V
Έκδοση: (2010)

Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids.
ανά: Pei, B, κ.ά.
Έκδοση: (2011)

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
ανά: De Santo, C, κ.ά.
Έκδοση: (2008)

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
ανά: De Santo, C, κ.ά.
Έκδοση: (2008)

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells.
ανά: Kotsianidis, I, κ.ά.
Έκδοση: (2005)

The role of invariant NKT cells at the interface of innate and adaptive immunity.
ανά: Cerundolo, V, κ.ά.
Έκδοση: (2010)

CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.
ανά: Barral, P, κ.ά.
Έκδοση: (2010)

The role of invariant NKT cells in enhancing antigen specific T and B cell responses
ανά: Cerundolo, V
Έκδοση: (2005)

The actin cytoskeleton modulates the activation of invariant NKT cells by segregating CD1d nanoclusters on antigen presenting cells
ανά: Cerundolo, V, κ.ά.
Έκδοση: (2016)

Synthetic iNKT cell-agonists as vaccine adjuvants--finding the balance.
ανά: Cerundolo, V, κ.ά.
Έκδοση: (2010)

Harnessing invariant NKT-cells to enhance antigen specific immune responses
ανά: Cerundolo, V
Έκδοση: (2014)

TCR signal strength controls thymic differentiation of iNKT cell subsets
ανά: Kathryn D. Tuttle, κ.ά.
Έκδοση: (2018-07-01)

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells.
ανά: Kotsianidis, I, κ.ά.
Έκδοση: (2006)

NKT Cells in Sepsis
ανά: Briana Leung, κ.ά.
Έκδοση: (2010-01-01)

The role of invariant natural killer T (iNKT) cells in modulating the lung inflammatory response during influenza A virus infection
ανά: McEwen-Smith, R, κ.ά.
Έκδοση: (2013)

Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells
ανά: Samanta Melgar-Rodríguez, κ.ά.
Έκδοση: (2021-01-01)

Role of NKT Cells during Viral Infection and the Development of NKT Cell-Based Nanovaccines
ανά: Masood Alam Khan, κ.ά.
Έκδοση: (2021-08-01)

Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
ανά: Porubsky, S, κ.ά.
Έκδοση: (2012)

Modulation of TCR signalling components occurs prior to positive selection and lineage commitment in iNKT cells
ανά: Xuyen T. Dinh, κ.ά.
Έκδοση: (2021-12-01)

DOCK8 is critical for the survival and function of NKT cells.
ανά: Crawford, G, κ.ά.
Έκδοση: (2013)

The Role of NKT Cells in Glioblastoma
ανά: Emily E. S. Brettschneider, κ.ά.
Έκδοση: (2021-06-01)