Probing biomolecular structures and dynamics of single molecules using in-gel alternating-laser excitation.

Gel electrophoresis is a standard biochemical technique used for separating biomolecules on the basis of size and charge. Despite the use of gels in early single-molecule experiments, gel electrophoresis has not been widely adopted for single-molecule fluorescence spectroscopy. We present a novel me...

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Autori principali: Santoso, Y, Kapanidis, A
Natura: Journal article
Lingua:English
Pubblicazione: 2009