Bisphosphonate affinity to hydroxyapatite and farnesyl pyrophosphate inhibitory potency, together, drive in vivo efficacy

Ижил төстэй зүйлс

• Predicting the clinical potencies of bisphosphonates: Divergence of hydroxyapatite and farnesyl diphosphate synthase binding affinities
  -н: Xia, Z, зэрэг
  Хэвлэсэн: (2007)
• The mode of binding of nitrogen containing bisphosphonates in farnesyl pyrophosphate synthase
  -н: Ebetino, F, зэрэг
  Хэвлэсэн: (2007)
• A mirror image pair of bisphosphonate analogs further demonstrates the mode of binding of the bisphosphonates in farnesyl pyrophosphate synthase
  -н: Ebetino, F, зэрэг
  Хэвлэсэн: (2008)
• Refining structure activity relationships among nitrogen containing bisphosphonates: Dissociation of mineral binding affinity and inhibitory potency on farnesyl diphosphate synthase.
  -н: Xia, Z, зэрэг
  Хэвлэсэн: (2006)
• Analysis of the kinetic mechanism of inhibition of Farnesyl Pyrophosphate Synthase by nitrogen containing bisphosphonates.
  -н: Dunford, J, зэрэг
  Хэвлэсэн: (2006)