Cell proliferation is a key determinant of the outcome of FOXO3a activation.

The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases aff...

詳細記述

書誌詳細
主要な著者: Poulsen, R, Carr, A, Hulley, P
フォーマット: Journal article
言語:English
出版事項: 2015