Cell proliferation is a key determinant of the outcome of FOXO3a activation.

The FOXO family of forkhead transcription factors have a pivotal role in determining cell fate in response to oxidative stress. FOXO activity can either promote cell survival or induce cell death. Increased FOXO-mediated cell death has been implicated in the pathogenesis of degenerative diseases aff...

Полное описание

Библиографические подробности
Главные авторы: Poulsen, R, Carr, A, Hulley, P
Формат: Journal article
Язык:English
Опубликовано: 2015