Structure of three tandem filamin domains reveals auto-inhibition of ligand binding.

Structure of three tandem filamin domains reveals auto-inhibition of ligand binding.

Show other versions (1)

Human filamins are large actin-crosslinking proteins composed of an N-terminal actin-binding domain followed by 24 Ig-like domains (IgFLNs), which interact with numerous transmembrane receptors and cytosolic signaling proteins. Here we report the 2.5 A resolution structure of a three-domain fragment...

Descrición completa

Detalles Bibliográficos
Main Authors: Lad, Y, Kiema, T, Jiang, P, Pentikäinen, O, Coles, C, Campbell, I, Calderwood, D, Ylänne, J
Formato: Journal article
Idioma:English
Publicado: 2007

Títulos similares

Títulos similares