Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants
AA disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-4 (ADAMTS-4) and ADAMTS-5 are zinc-dependent metalloproteinases that are involved in the maintenance of cartilage extracellular matrix (ECM) and are currently considered the major aggrecanases in the development of osteoarth...
Hauptverfasser: | Fowkes, MM, Lim, NH |
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Weitere Verfasser: | Apte, SS |
Format: | Book section |
Sprache: | English |
Veröffentlicht: |
Humana Press
2019
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