Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

AA disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-4 (ADAMTS-4) and ADAMTS-5 are zinc-dependent metalloproteinases that are involved in the maintenance of cartilage extracellular matrix (ECM) and are currently considered the major aggrecanases in the development of osteoarth...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Fowkes, MM, Lim, NH
Rannpháirtithe:	Apte, SS
Formáid:	Book section
Teanga:	English
Foilsithe / Cruthaithe:	Humana Press 2019

Míreanna comhchosúla

Screening for selective ADAMTS-5 substrates to monitor proteinase activity
de réir: Fowkes, MM
Foilsithe / Cruthaithe: (2021)

Development of selective ADAMTS-5 peptide substrates to monitor proteinase activity
de réir: Fowkes, MM, et al.
Foilsithe / Cruthaithe: (2023)

Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity.
de réir: Fushimi, K, et al.
Foilsithe / Cruthaithe: (2008)

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
de réir: Gendron, C, et al.
Foilsithe / Cruthaithe: (2007)

Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications.
de réir: Lim, N, et al.
Foilsithe / Cruthaithe: (2010)

The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.
de réir: Troeberg, L, et al.
Foilsithe / Cruthaithe: (2009)

ADAMTS4 and ADAMTS5 are upregulated early in the DMM model of murine OA
de réir: Burleigh, A, et al.
Foilsithe / Cruthaithe: (2009)

Engineering and expression of ADAMTS-4 and ADAMTS-5, proteolytic enzymes involved in osteoarthritis progression
de réir: Lauer-Fields, J, et al.
Foilsithe / Cruthaithe: (2005)

Serum Level of ADAMTS4 and ADAMTS8 in Patients with Psoriatic Arthritis
de réir: Irmak Icen Taskin, et al.
Foilsithe / Cruthaithe: (2020-12-01)

ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis
de réir: Laura Dupont, et al.
Foilsithe / Cruthaithe: (2022-04-01)

The ADAMTS/Fibrillin Connection: Insights into the Biological Functions of ADAMTS10 and ADAMTS17 and Their Respective Sister Proteases
de réir: Stylianos Z. Karoulias, et al.
Foilsithe / Cruthaithe: (2020-04-01)

Cleavage of Fibulin-2 by the aggrecanases ADAMTS-4 and ADAMTS-5 contributes to the tumorigenic potential of breast cancer cells
de réir: Fontanil, T, et al.
Foilsithe / Cruthaithe: (2017)

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels
de réir: Qianyi Ma, et al.
Foilsithe / Cruthaithe: (2017-06-01)

ADAMTS-5: The story so far
de réir: A J Fosang, et al.
Foilsithe / Cruthaithe: (2008-02-01)

Investigation of the endocytic pathway of ADAMTS-4
de réir: Owen, K, et al.
Foilsithe / Cruthaithe: (2009)

Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
de réir: Yamamoto, K, et al.
Foilsithe / Cruthaithe: (2014)

Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura
de réir: X. Long Zheng, et al.
Foilsithe / Cruthaithe: (2010-09-01)

Regulation of ADAMTS Proteases
de réir: Keron W. J. Rose, et al.
Foilsithe / Cruthaithe: (2021-06-01)

Acquired thrombotic thrombocytopenic purpura: ADAMTS13 activity, anti-ADAMTS13 autoantibodies and risk of recurrent disease
de réir: Bernhard Lämmle, et al.
Foilsithe / Cruthaithe: (2008-02-01)

Disappearing acts of ADAMTS13
de réir: Jan Voorberg, et al.
Foilsithe / Cruthaithe: (2015-08-01)

Determination of ADAMTS13 and Its Clinical Significance for ADAMTS13 Supplementation Therapy to Improve the Survival of Patients with Decompensated Liver Cirrhosis
de réir: Masahito Uemura, et al.
Foilsithe / Cruthaithe: (2011-01-01)

Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide
de réir: Salvatore Santamaria, et al.
Foilsithe / Cruthaithe: (2021-01-01)

Functional role of ADAMTS5 in adiposity and metabolic health.
de réir: Dries Bauters, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Ocular pulse amplitude (OPA) in canine ADAMTS10-open-angle glaucoma (ADAMTS10-OAG)
de réir: Vanessa A. Raphtis, et al.
Foilsithe / Cruthaithe: (2023-12-01)

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice
de réir: Naamah L. Zitomersky, et al.
Foilsithe / Cruthaithe: (2017-06-01)

Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura
de réir: Rahel Froehlich-Zahnd, et al.
Foilsithe / Cruthaithe: (2012-02-01)

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing.
de réir: Kashiwagi, M, et al.
Foilsithe / Cruthaithe: (2004)

ADAMTS proteases in cardiovascular physiology and disease
de réir: Salvatore Santamaria, et al.
Foilsithe / Cruthaithe: (2020-12-01)

Interleukin-1α induces ADAMTS-mediated aggrecanolysis in the bovine meniscus: evidence for a primary role of ADAMTS-4 in meniscus destruction
de réir: Lemke, Angelika K., et al.
Foilsithe / Cruthaithe: (2012)

ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
de réir: Flora Peyvandi, et al.
Foilsithe / Cruthaithe: (2008-02-01)

In vivo N-Terminomics Highlights Novel Functions of ADAMTS2 and ADAMTS14 in Skin Collagen Matrix Building
de réir: Cédric Leduc, et al.
Foilsithe / Cruthaithe: (2021-03-01)

Assay for ADAMTS-13 Activity with Flow Cytometric Readout
de réir: Jens Müller, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis
de réir: Xindie Zhou, et al.
Foilsithe / Cruthaithe: (2019-01-01)

The first deletion mutation in the TSP1-6 repeat domain of ADAMTS13 in a family with inherited thrombotic thrombocytopenic purpura
de réir: Roberta Palla, et al.
Foilsithe / Cruthaithe: (2009-02-01)

ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration
de réir: Timothy J. Mead, et al.
Foilsithe / Cruthaithe: (2025-03-01)

Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage
de réir: Takuya Tajima, et al.
Foilsithe / Cruthaithe: (2017-11-01)

The Function and Roles of ADAMTS-7 in Inflammatory Diseases
de réir: Yuying Zhang, et al.
Foilsithe / Cruthaithe: (2015-01-01)

The Mechanism and Role of ADAMTS Protein Family in Osteoarthritis
de réir: Ting Li, et al.
Foilsithe / Cruthaithe: (2022-07-01)

Expression and prognosis of ADAMTS18 in different tumors
de réir: Wenfei Guo, et al.
Foilsithe / Cruthaithe: (2024-02-01)

ADAMTS Proteins and Vascular Remodeling in Aortic Aneurysms
de réir: Zakaria Mougin, et al.
Foilsithe / Cruthaithe: (2021-12-01)