Purification and activity determination of ADAMTS-4 and ADAMTS-5 and their domain deleted mutants

AA disintegrin-like and metalloproteinase with thrombospondin type-1 motifs-4 (ADAMTS-4) and ADAMTS-5 are zinc-dependent metalloproteinases that are involved in the maintenance of cartilage extracellular matrix (ECM) and are currently considered the major aggrecanases in the development of osteoarth...

Полное описание

Библиографические подробности
Главные авторы: Fowkes, MM, Lim, NH
Другие авторы: Apte, SS
Формат: Book section
Язык:English
Опубликовано: Humana Press 2019