Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration

Runx1 is a transcription factor that plays a key role in determining the proliferative and differential state of multiple cell types, during both development and adulthood. Here, we report how Runx1 is specifically upregulated at the injury site during zebrafish heart regeneration, and that absence...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Koth, J, Wang, X, Killen, AC, Stockdale, W, Potts, HG, Jefferson, A, Bonkhofer, F, Riley, P, Patient, R, Göttgens, B, Mommersteeg, M
Materialtyp: Journal article
Språk:English
Publicerad: Company of Biologists 2020