Using chemical genetics and ATP analogues to dissect protein kinase function.

Protein kinases catalyze the transfer of the gamma-phosphate of ATP to a protein substrate and thereby profoundly alter the properties of the phosphorylated protein. The identification of the substrates of protein kinases has proven to be a very difficult task because of the multitude of structurall...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Elphick, L, Lee, SE, Gouverneur, V, Mann, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2007