Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

Enhancing protective immunity to malaria with a highly immunogenic virus-like particle vaccine

The leading malaria vaccine in development is the circumsporozoite (CS) protein-based vaccine, RTS,S, which targets the pre-erythrocytic stage of Plasmodium falciparum infection. It induces modest levels of protective efficacy largely mediated by CS specific antibodies. We aimed to enhance vaccine e...

書誌詳細
主要な著者:	Gilbert, S, Collins, K, Snaith, R, Cottingham, M, Hill, A
フォーマット:	Journal article
出版事項:	Nature Publishing Group 2017

類似資料

Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity
著者:: Chauveau, L, 等
出版事項: (2021)

Virus-Like Particles as an Immunogenic Platform for Cancer Vaccines
著者:: Jerri C. Caldeira, 等
出版事項: (2020-04-01)

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara.
著者:: Schneider, J, 等
出版事項: (1998)

Virus-like particles as vaccine adjuvants.
著者:: Gilbert, S
出版事項: (2001)

Gene gun intradermal DNA immunization followed by boosting with modified vaccinia virus Ankara: enhanced CD8+ T cell immunogenicity and protective efficacy in the influenza and malaria models.
著者:: Dégano, P, 等
出版事項: (1999)

Protein particle vaccines against malaria.
著者:: Gilbert, S, 等
出版事項: (1997)

Virus-like particle vaccines
著者:: Mukhopadhyay, E, 等
出版事項: (2022)

Safety and immunogenicity of DNA/modified vaccinia virus ankara malaria vaccination in African adults.
著者:: Moorthy, V, 等
出版事項: (2003)

Pigs Immunized with the Virus-like Particle Vaccine Are Protected against the Hepatitis E-3 Virus
著者:: Hyeon-Jeong Go, 等
出版事項: (2021-11-01)

Phage-like particle vaccines are highly immunogenic and protect against pathogenic coronavirus infection and disease
著者:: Bennett J. Davenport, 等
出版事項: (2022-05-01)

Virus-like Particle Vaccines of Infectious Bursal Disease Virus Expressed in <i>Escherichia coli</i> Are Highly Immunogenic and Protect against Virulent Strain
著者:: Pengchao Ji, 等
出版事項: (2023-10-01)

Immunization with Virus-Like Particle Vaccine Protects Rabbits against Hepatitis E-3 Virus Infection
著者:: Hyeon-Jeong Go, 等
出版事項: (2022-06-01)

Complete protective immunity against blood-stage malaria induced by heterologous prime-boost vaccination
著者:: Draper, S, 等
出版事項: (2005)

Immunogenicity and protective efficacy of a novel bacterium-like particle-based vaccine displaying canine distemper virus antigens in mice and dogs
著者:: Jianzhong Wang, 等
出版事項: (2024-04-01)

Enhanced immunogenicity of CD4(+) t-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis.
著者:: Mcshane, H, 等
出版事項: (2001)

Ty virus-like particles, DNA vaccines and Modified Vaccinia Virus Ankara; comparisons and combinations.
著者:: Gilbert, S, 等
出版事項: (1999)

Immunogenicity and protective efficacy of human metapneumovirus virus-like particles produced by a recombinant baculovirus in mice
著者:: Fenlian Ma, 等
出版事項: (2023-10-01)

A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity.
著者:: Ambühl, P, 等
出版事項: (2007)

A Preclinical Immunogenicity Study of the Recombinant Human Papillomavirus Nine-Valent Virus-like Particle Vaccine
著者:: Dan Xu, 等
出版事項: (2024-11-01)

Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines.
著者:: Draper, S, 等
出版事項: (2010)

Virus-like particle (VLP) plus microcrystalline tyrosine (MCT) adjuvants enhance vaccine efficacy improving T and B cell immunogenicity and protection against Plasmodium berghei/vivax
著者:: Cabral-Miranda, G, 等
出版事項: (2017)

Improved systems for generating and evaluating adenovirus vaccine vectors reveal differences in immunogenicity between vectors of different adenoviral species
著者:: Dicks, M, 等
出版事項: (2011)

Potent Protective Immune Responses to <i>Senecavirus</i> Induced by Virus-Like Particle Vaccine in Pigs
著者:: Suyu Mu, 等
出版事項: (2020-09-01)

Enhanced CD8 T cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes.
著者:: Gilbert, S, 等
出版事項: (2002)

The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirus.
著者:: de Cassan, S, 等
出版事項: (2011)

Immunogenicity of vaccines for malaria-exposed populations
著者:: Bowyer, GSA
出版事項: (2018)

Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses
著者:: Katrin Kramer, 等
出版事項: (2019-01-01)

Anti-CD25 antibody enhancement of vaccine-induced immunogenicity: increased durable cellular immunity with reduced immunodominance.
著者:: Moore, A, 等
出版事項: (2005)

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein
著者:: Kim, YC, 等
出版事項: (2024)

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein
著者:: Young Chan Kim, 等
出版事項: (2024-12-01)

Construction of Porcine Epidemic Diarrhea Virus-Like Particles and Its Immunogenicity in Mice
著者:: Jihee Kim, 等
出版事項: (2021-04-01)

Immunogenicity of Plant-Produced Human Papillomavirus (HPV) Virus-Like Particles (VLPs)
著者:: Paulina N. Naupu, 等
出版事項: (2020-12-01)

Preclinical antihypertensive efficacy and immunogenicity in humans of a vaccine against angiotensin II based on virus-like particles (VLPs)
著者:: Tissot, A, 等
出版事項: (2005)

Immunogenicity and Efficacy of Monovalent and Bivalent Formulations of a Virus-Like Particle Vaccine against SARS-CoV-2
著者:: Matthew D. Resch, 等
出版事項: (2022-11-01)

Immunogenicity of HIV-1 Vaccines Expressing Chimeric Envelope Glycoproteins on the Surface of Pr55 Gag Virus-Like Particles
著者:: Rosamund Chapman, 等
出版事項: (2020-01-01)

Safety and immunogenicity of heterologous prime-boost immunization with viral-vectored malaria vaccines adjuvanted with Matrix-M
著者:: Venkatraman, N, 等
出版事項: (2017)

Uncovering the mechanisms of adenovirus vector immunogenicity
著者:: Dicks, M, 等
出版事項: (2013)

Immunogenicity and Protective Effect of a Virus-Like Particle Containing the SAG1 Antigen of <i>Toxoplasma gondii</i> as a Potential Vaccine Candidate for Toxoplasmosis
著者:: Won Hyung Choi, 等
出版事項: (2020-04-01)

Allergens displayed on virus-like particles are highly immunogenic but fail to activate human mast cells.
著者:: Engeroff, P, 等
出版事項: (2017)

A protein particle vaccine containing multiple malaria epitopes.
著者:: Gilbert, S, 等
出版事項: (1997)