Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.

Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.

We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...

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Detalhes bibliográficos
Main Authors:	Lennerstrand, J, Stammers, D, Larder, B
Formato:	Journal article
Idioma:	English
Publicado em:	2001

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