Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.
We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...
Главные авторы: | Lennerstrand, J, Stammers, D, Larder, B |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2001
|
Схожие документы
-
Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.
по: Lennerstrand, J, и др.
Опубликовано: (2001) -
Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
по: Chamberlain, P, и др.
Опубликовано: (2002) -
A mutation in the 3' region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverse transcriptase inhibitor resistance.
по: Harrigan, P, и др.
Опубликовано: (2002) -
STRUCTURAL STUDIES ON HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE
по: Stammers, D, и др.
Опубликовано: (1990) -
THE GROWTH AND CHARACTERIZATION OF CRYSTALS OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REVERSE-TRANSCRIPTASE
по: Jones, E, и др.
Опубликовано: (1993)