Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.
We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...
Autores principales: | Lennerstrand, J, Stammers, D, Larder, B |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2001
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